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Comparison Measurements: eSense Skin Response vs. NeXus-4 & Shimmer3

In April 2018, Mindfield Biosystems conducted systematic comparison measurements between the eSense Skin Response and two established reference systems. The results show that the eSense matches the precision of significantly more expensive clinical systems.

Methodology

All measurements were performed on the same subject, with both devices attached simultaneously to the same hand. Electrode positions were swapped between measurements to control for position-related differences.

Property eSense Skin Response NeXus-4 Shimmer3 GSR
Manufacturer Mindfield Biosystems Mind Media Consensys/Shimmer
Type Wired sensor (smartphone microphone input) 4-channel clinical system Research wearable
Certification CE CE IIa, FDA registered CE
Sampling rate 10 Hz 32 Hz 10 Hz
Software eSense App v2.1.0 BioTrace V2017A Consensys
Price range €169 (Bundle) approx. €3,000–5,000 (discontinued) from €650

Electrodes: Medical single-use gel electrodes (identical gel quality), changed after each measurement. Display: Samsung Galaxy Tab S2 (SM-T819, Android 7.0).

Measurement Setup

Simultaneous electrode placement: eSense (white connectors) and reference device (black connectors) on the same hand

Reference Devices

NeXus-4 (Mind Media)
NeXus-4 (Mind Media)

Shimmer3 GSR (Consensys/Shimmer)
Shimmer3 GSR

Results: eSense vs. NeXus-4

Two 10-minute measurements with simultaneous recording. Electrode positions were swapped between measurements (index/middle finger vs. ring/little finger).

Measurement 3: NeXus-4 on index/middle finger, eSense on ring/little finger

Overlay chart: eSense Skin Response (blue) vs. NeXus-4 (orange), measurement 3 – both curves overlaid

Both curves show good agreement in waveform shape. Absolute amplitudes differ due to the different finger positions.

Measurement 4: Positions swapped

Overlay chart: eSense Skin Response (blue) vs. NeXus-4 (orange), measurement 4 (positions swapped)

Observation: The device on the index/middle finger consistently shows smaller amplitudes than the one on the ring/little finger — regardless of which device is in which position. The cause: increased keratinization of more frequently used fingers from typing and writing.

Results: eSense vs. Shimmer3 GSR

Two additional 10-minute measurements with the Shimmer3 GSR as reference.

Measurement 5: Simultaneous recording

Overlay chart: eSense Skin Response (blue) vs. Shimmer3 GSR (green), measurement 5 – both curves overlaid

Both systems track the same physiological events in the same temporal sequence. Absolute values differ due to different electrode positions, but the pattern of skin conductance changes is exactly comparable.

Conclusion

Comparison Results

The comparison measurements show that absolute amplitude depends on many factors — device, measurement method, electrode position, and skin characteristics. However, it is clearly evident that changes in skin conductance are recorded exactly and comparably by all systems. The eSense Skin Response matches the precision of significantly more expensive systems.

The eSense Skin Response thus fulfills its purpose of enabling optimal biofeedback training and is suitable for scientific studies — as confirmed by the independent validation by Emory University (r = 0.94) and additional peer-reviewed studies.

Downloads

Download the complete report and raw data:

Note

These comparison measurements were conducted by Mindfield Biosystems in their own laboratory. For independent scientific validation, see Hinrichs et al. 2017 (Emory University), who found a correlation of r = 0.94 with the clinical lab standard Biopac.