Kubios HRV Scientific

Kubios HRV Scientific

ubios HRV Scientific is a leading software for heart rate variability (HRV) analysis software for scientific research and professional use. It provides detailed HRV analysis with over 40 analysis parameters. For example, it includes an accurate QRS detector and an automatic correction algorithm to guarantee high quality HRV data in all conditions. NEW in version 4.3: Completely modernized user interface with dark mode and new Kubios Data Browser for efficient measurement management directly from the software. Mindfield is the official German distribution partner for the HRV Scientific Software. We offer the software for the same price as Kubios but on top of that we offer the support in German language. We offer a 7-day trial version for Scientific and a 14-day trial version for Team Readiness (for the Small License) on request. If you like it, you can purchase the license and use this trial version directly. Please contact us via email.

Exclusive to the Scientific Version

Supports measurements with the Kubios HRV Mobile App. Use the custom measurement mode of the Kubios HRV Mobile App and synchronize your recordings with your PC via the Kubios Cloud
Support for additional data channels (display of additional channels on data axes)
ECG waveform analysis (QRS duration, QT and QTc times, and P, Q, R, S, and T amplitudes).
Training data analytics with detailed performance metrics (HR, RESP, TRIMP, ventilatory thresholds and VO2) and heart rate recovery
Selection of animal species (rat, mouse and pig) for preclinical researchers.

Also new: academic and commercial license

The Kubios HRV Scientific software is available in 2 different versions: Once an academic license which may not be used for commercial purposes and therefore has a lower price. For commercial purposes there is the regular commercial license.

Compatible with all Mindfield MindMaster devices

The Kubios HRV Scientific software is compatible with all our Mindfield MindMaster devices.. You can analyze and evaluate all ECG and pulse data from the MindMaster with Kubios.

Compatible with the eSense Pulse

Especially interesting is the combination of the Kubios software with the eSense Pulse, our HRV biofeedback device. Thanks to over 40 analysis parameters, HRV data measured with the eSense Pulse can be evaluated particularly well. This makes Kubios interesting for professional biofeedback trainers. Furthermore, Kubios HRV Scientific software can even be used for scientific research.

For scientific research

Kubios HRV is a scientifically validated software and is being widely used in both clinical and pre-clinical research. The software has been developed over more than 20 years by experienced medical physicists. The software was originally published in 2004 and underwent a significant update in 2014. These two publications have attracted many citations (Google Scholar citations).

Stress and recovery monitoring

Kubios HRV Scientific provides detailed monitoring of the autonomic nervous system – ideal for analyzing stress, recovery, and training effects.

Images of the software

Downloads Kubios HRV Scientific

Kubios HRV Scientific Brochure (PDF)

Available in the Mindfield Shop

You can purchase the Kubios HRV Scientific software from our online shop for the same price as Kubios, but we also offer additional and exclusive support in German. With us you can choose both the academic license as well as the commercial license.

Kubios writes about the license:

Kubios HRV Scientific (always the latest version, currently v4.3.0) for Windows (Win 10 or 11, 64-bit) and macOS. A single user subscription license (1-year subscription) including access to Kubios HRV mobile app data, software updates, and technical support. One license allows you to use Kubios HRV Scientific on one computer at a time. “Academic License” shall mean a license, which has been purchased at a price (“Academic Price”) offered only to academic organizations and other not-for-profit organizations as well as to individuals for the purpose of using the Software only for Academic Use and/or Personal Use. Kubios HRV Scientific replaces the former Kubios HRV Premium.

Supports your measurement device

Kubios HRV Scientific is compatible with several commonly used electrocardiogram (ECG) devices and with most of the HR monitors on the market. The only requirement for the HR monitor is that it can record inter-beat interval (IBI) data.

Operating system

Kubios HRV Scientific is available for 64-bit operating systems: Windows 10 & 11, macOS.
Minimum system requirements: 8 GB RAM (16 GB recommended), 3-5 GB hard disk space and screen resolution 1024 x 768 or higher

Usability

Easy-to-use graphical user interface (GUI)
Adaptable to user needs due to adjustable analysis settings through software preferences

Supported data formats and devices

Inter-beat-interval (IBI) or RR interval files: Garmin and Suunto FIT files; Polar TXT files; custom text and CSV files.
ECG/PPG files: European Data Format (EDF/EDF+); Cardiology XML; ISHNE Holter ECG Data Format; Biopac ACQ3; General Data Format (GDF); and custom text and CSV files.
Supported ECG/PPG devices: Actiheart 5, AliveCor Kardia, Biopac, Bittium Faros, Cortrium C3+, Empatica E4, GE CardioSoft, Hexoskin, Mindfield MindMaster, Movesense ECG, Shimmer and various clinical Holter and ECG monitors.
Supported HR monitors: Firstbeat Bodyguard 3, Garmin (Forerunner and Fenix series), Polar H10, Polar Verity Sense, Suunto and other Bluetooth HR sensors with RR interval recording

Preprocessing functions

Built-in QRS detector for accurate ECG R-wave acquisition and pulse wave detector for PPG data
Automatic correction algorithm to correct missed, extra and misaligned beats from RR interval time series. The algorithm was validated using the MIT-BIH arrhythmia database, which shows 97.0% accuracy in detecting ectopic beats and 99.9% accuracy in identifying normal beats
Smoothness prior method for removing very low frequency trend components when performing short term HRV analyses.

Features of HRV analysis

Stress level and indices of parasympathetic (PNS) and sympathetic nervous system (SNS) activities.
Time domain parameters: Mean RR and HR, min. and max. HR, SDNN, RMSSD, pNN50 (with adjustable threshold), HRV triangular index and TINN.
Parameters in the frequency domain: Welch’s/Lomb-Scargle periodogram and AR spectrum estimates. VLF, LF and HF peak frequencies and bandpower as well as LF/HF ratio
Nonlinear parameters: Poincaré plot (SD1, SD2 and SD2/SD1), ApEn, SampEn, Detrended fluctuation analysis (DFA), Recurrence plot analysis (RPA) and Multiscale entropy (MSE)
Support for additional data channels (display of additional channels on data axes)
ECG waveform analysis (QRS duration, QT and QTc times, and P, Q, R, S, and T amplitudes).
Training data analysis with detailed performance metrics (HR, RESP, TRIMP, ventilatory thresholds, and VO2) and heart rate recovery

Respiratory sinus arrhythmia (RSA) estimation.

Built-in ECG-based respiration (EDR) algorithm that provides accurate respiration rate estimation required for reliable RSA component estimation (to ensure respiration rate is within the RF band) and individual resonant frequency assessment

Time-variable analysis functions

Time evolution of HRV parameters to detect changes in HRV e.g. during a 24-hour recording or during training and recovery phases
Analysis window for the investigation of long-term or short-term dynamics adjustable
Spectrogram with “fire” color map, a graphical representation of the dynamic changes of HRV components. At a glance, you can see how stress alters the cardiovascular system and how therapeutic measures can speed recovery

Export reports and results

ECG printout option to print the ECG signal (single lead) on a standard paper ECG layout.
PDF reports with detailed HRV analysis results and graphs
Text file export to save all analysis results into a structured text file
Matlab MAT file export to save the analysis session and results. The previously run analysis session can be reopened by opening the MAT file, which provides an easy way to change the analysis settings and re-analyze the data
“SPSS friendly” batch file export to save analysis results to a CSV file that can be opened in Excel or imported into SPSS

Changelog Kubios HRV Scientific 4.3.0

(released 10.03.2026) New Features:

New user interface and dark mode: The entire user interface has been modernized with updated UI components. Kubios HRV Scientific now supports dark mode, and info buttons have been added to main functionalities.^Lite
Kubios Data Browser: Easily manage the measurements you’ve recorded with the Kubios HRV app! Browse your Kubios Cloud data to quickly open measurements for analysis, download them to your computer, or export them as CSV or EDF files.
Enhanced time synchronization: Added support for channel-specific timestamps within measurement data, significantly improving time synchronization and reliability of longer-term recordings.

Improvements and bug fixes:

Added an option to display RR interval values (in milliseconds) directly on the ECG printout.
Improved logic for navigating through event markers.
Improved keyboard navigation with Ctrl/Cmd + arrow keys for faster navigation.^Lite
Other minor bug fixes and improvements, including accessibility enhancements.^Lite

Changelog Kubios HRV Scientific 4.2.0

(released 19.06.2025)

Export HRV figures – Easily generate high-resolution visuals for publications and presentations
FIT file performance data support in Training Report – Analyze performance metrics like speed, power, and altitude
Import event markers – Add pre-coded events via CSV template
Improved signal handling – More robust ECG and QRS detection for enhanced accuracy
Refined test analytics – Enhanced calculation of the head-up tilt test 30:15 ratio
Minor bug fixes and accessibility updates for a smoother user experience

Changelog Kubios HRV Scientific 4.1.2

(released 9.10.2024, “Lite” tag indicates that the update or improvement is also applicable to the Lite version).

Time-varying and sample-based HRV analysis optimized for significant performance improvements.
Faster manual beat detection editing by disabling beat correction algorithm during manual edits.
Minor updates to CSV file support and support for rat PPG data.
Logging support added to help troubleshoot error situations.^Lite To enable logging:
1. Log out from the software (File menu →User → Sign out) to reach the login screen.
2. Click the settings icon, check Enable logging, and choose a file for storing logs.
Added web proxy support. Proxy settings can be configured from the login screen, in the same location where logging is enabled.^Lite
Other minor bug fixes and improvements.^Lite

You can find the complete changelog with older changes at https://www.kubios.com/release-notes/

Kubios HRV Scientific